Evidence
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Higher-order representations offer one route to this end: hypergraphlets applied to hypernetworks in which nodes are proteins and hyperedges encode protein–protein interactions, complexes, or signaling pathways can test whether such topology carries biological information beyond that recoverable from pairwise PPI networks.
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Higher order molecular organisation as a source of biological function
We investigate biological hypernetworks in which nodes are proteins and hyperedges capture PPIs, protein complexes, or signaling pathways. The main aim is to check if the topology of these hypernetwork representations of the data carries biological information that goes beyond the information that c…
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We investigate biological hypernetworks in which nodes are proteins and hyperedges capture PPIs, protein complexes, or signaling pathways. The main aim is to check if the topology of these hypernetwork representations of the data carries biological information that goes beyond the information that can be obtained from PPI networks. We use hypergraphlets in this investigation.